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25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines

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When endogenous synthesis is insufficient or rapidly depleted, supplementation through injectable formulations becomes clinically relevant

Presented for research literature review only Irie HY et al

1.3.1 Polymeric nanosystems Polymeric NPs may be functionalized and retained for months, and the physicochemical characteristics of these carriers could regulate drug release [89]

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