Dulaglutide (Trulicity) Strengths: Once-weekly dosing Easy-to-use auto-injector device Proven cardiovascular benefit Good tolerability profile Considerations: Less weight loss than semaglutide Moderate (not maximum) glucose efficacy Best for: Patients prioritizing convenience and tolerability over maximum efficacy
Moiz A, Filion KB, Toutounchi H, et al
Neuro Endocrinology Letters
Am Fam Physician 102:627628 Gerstein HC, Colhoun HM, Dagenais GR, et al (2019) Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
Historically, a physician could decide that he or she wanted to treat a patient with a certain drug and give it in a certain route of administration
The hypothalamus and the control of energy homeostasis: Different circuits, different purposes