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Expansile dermal nests with diffuse cytologic atypia, lack of maturation with depth, significant pagetoid spread of intraepidermal melanocytes, effacement of the epidermis, conspicuous mitoses, and asymmetry should all prompt concern for melanoma

PMID: 26367736 [26] Dinkova-Kostova AT, Holtzclaw WD, Cole RN, et al

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General Food Advice Metformin should be taken with or just after a meal or snack

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Why FDA Classification and Drug Schedule Matter for Safety Mounjaro is a non-controlled (Schedule V) prescription medication, meaning it carries lower regulatory burden than controlled substances but still requires medical supervision