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The functional prediction performed using phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt) and Kyoto encyclopedia of genes and genomes (KEGG) implicated that the depleted gut microbiome was associated with metabolic pathways, including those related to carbohydrates, butanoate, and amino acids (Supplementary Fig
Metformin enhances mitophagy and mitochondrial function, contributing to improved glucose and lipid metabolism
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Accessed 7 July 2021
Specifically, for each unit reduction in BMI, whole-body fat mass decreases by about 7.9 kg, while muscle mass reduces by about 6.4 kg
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