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Statements Author contributions AF, EDY and RS discussed the concepts and pitfalls, and wrote the manuscript

10.1016/j.yexcr.2021.112932 131 XieY.SongX.SunX.HuangJ.ZhongM.LotzeM

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Despite the use of rodents and small mammals being commonplace in research, in particular for the development of novel therapeutic agents, caution still needs to be practiced when extrapolating research data to clinical applications