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KCCQ-CSS = Kansas City Cardiomyopathy Questionnaire Clinical Summary Score

If you watched the Super Bowl in 2026, you likely saw Serena Williams share her weight loss journey on GLP-1 medications in a commercial

Retatrutide-induced weight loss may raise sex hormone-binding globulin (SHBG) levels, altering the ratio of free to total testosterone

Even though the medication continues to help regulate appetite, those behind-the-scenes changes can shrink the calorie gap that once fueled steady weight loss

Never take two doses in the same week to make up for a missed one, as this increases the risk of side effects

Cost and access considerations represent practical limitations for many patients