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General function: Involved in nicotinamide N-methyltransferase activity Specific function: Putative nicotinamide N-methyltransferase involved in rDNA silencing and in lifespan determination Gene Name: NNT1 Uniprot ID: Q05874 Molecular weight: 29632.30078 Reactions General function: Involved in phosphatidylethanolamine N-methyltransferas Specific function: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine Gene Name: PEM1 Uniprot ID: P05374 Molecular weight: 101203.0 Reactions General function: Involved in identical protein binding Specific function: Specifically methylates guanosine-37 in various tRNAs

Pun PB, Lu J, Moochhala S

Owoade, Food Nutr

Oncostatic & Genomic Integrity Effects Epithalons potential oncostatic (anti-cancer) properties are supported by animal studies showing reductions in spontaneous tumor incidence and metastasis, especially among aged rodents [4]

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