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In another similar animal trial, the antioxidant treatment promoted the translocation of the transcription factor NRF2 to the nucleus and gene transcription of antioxidant enzymes, ultimately blocking epilepsy progression and producing neuroprotective effects (211)
Joint issues: TB-500 for systemic joint inflammation
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[] The brain-derived neurotrophic factor (BDNF) plays a key role in neural plasticity, influencing synaptogenesis through the control of synaptic dendritization and morphogenesis, promoting new neuronal circuit formation and improved cognitive performance
Overall, further mechanistic studies are needed in the future to validate the therapeutic potential of TNF- and the inhibitors and inducers of ferroptosis in EBV-related diseases
From the preclinical data for putative benefits there were also important side effects noted
