doi:10.1016/j.bcp.2017.11.007 (PMID 29155147) Neelakantan H, Brightwell CR, Graber TG, et al
Side effects are rare but can include mild discomfort at the injection site
Week 1-2: Adjustment phase The first two weeks primarily involve physiological adjustment rather than visible results
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Its use as a research tool should therefore be accompanied by target-confirmation experiments, pathway-specific metabolite monitoring, appropriate vehicle controls, lot-specific documentation, and safety endpoints matched to the study duration and biological model