For most people, waiting 12 years for a medication that may be marginally better doesnt make sense when an excellent option (tirzepatide) is available today
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In the first 8 weeks of GLP-1 dose escalation, whats the earliest sign that tells you protein intake is becoming inadequate
The GLP-1 receptor and GLP-1R and is a class B GPCR expressed at highest density on pancreatic beta cells with expression characterised across hypothalamic arcuate and paraventricular nuclei, brainstem nucleus tractus solitarius, nodose ganglion vagal afferents, cardiac myocytes, endothelial cells, and kidney
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