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doi: 10.1152/ajpendo.00017.2014 226 SuhSKimKW
The gastrointestinal adverse event profile of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes [abstract]
Key takeaways GLP-1 is often associated with weight-loss drugs, but this class of medications is named after a hormone that helps increase feelings of fullness and regulate blood sugar levels
However, intraperitoneal injection of TAK-242, an inhibitor of TLR4, protects tubular cell injury by suppressing GSDMD-related pyroptosis in db/db mice, and the expression of caspase-1 and GSDMD-NT were significantly decreased in renal cortex tissue (127)
Pregnancy, significant weight gain, and even significant weight loss can stretch the abdominal wall, leaving behind loose muscles, excess skin, and often a weakened core
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