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Key Takeaways NAD has been shown to support healthy aging and longevity

Taking oligonucleotide (oligo) as an example, the transport vehicle (TV) facilitates receptor-mediated transcytosis across the blood-brain barrier, while intrathecal (IT) administration enables drugs to bypass the BBB and directly reach the CNS

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Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10), extended with a C-terminal Pro-Gly-Pro tripeptide to improve metabolic stability

At weeks 1 and 6 post-STZ, STZ+FTS animals received IM injections of RAd-FTS

The main risks are skin irritation with high concentrations and the contamination concerns associated with poorly sourced or improperly prepared formulations