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Beta-Cell Function in Obesity: Effects of Weight Loss
Chodurek, and Z
Summary: Whether weight loss pills make you pee more depends on the type: supplements containing caffeine or natural diuretics can increase urination, while prescription medicines such as semaglutide and orlistat do not directly cause diuresis but may affect fluid balance through other mechanisms
If you hit a plateau on three times weekly dosing, returning to daily dosing is a reasonable first step before escalating the dose
A sensitized high-throughput screen identified a series of small molecule GLP-1R agonists that were optimized to promote endogenous GLP-1R signaling with nM potency
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