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Brookes MH, Golding BT, Howes DA, Hudson AT (1983) Proof that the absolute configuration of natural -lipoic acid is R by the synthesis of its enantiomer [( S )-()--lipoic acid] from ( S )-malic acid
Key takeaways: Standard dose: 12% topical serum nightly for skin/hair, 13 mg SC once daily for systemic/tendon recovery Best-in-class for collagen synthesis, ECM remodeling, and anti-inflammatory gene modulation Topical route dominates for aesthetics (skin/hair)
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