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Sleep disruption from hot flashes impairs leptin (fullness hormone) production, creating a cycle of increased appetite and reduced satiety signals
Correspondingly, adrenocortical cells express receptors for each of these factors ( In vitro studies found that vital glucose regulating-peptides also have the capacity to regulate ACTH-stimulated glucocorticoid secretion
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I was called "the mother of GLP-1," and I had a hard time with that for a long time
A meta-analysis of 311 Ewing sarcoma patients in multiple trials demonstrates that treatment with anti-IGF-IR mAb figitumumab, R1507, or ganitumab results in complete response in 0.7% cases, partial response in 11% cases, and stable diseases in 21% cases [154]
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