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Willard FS, Douros JD, Gabe MB, Showalter AD, Wainscott DB, Suter TM, Capozzi ME, van der Velden WJ, Stutsman C, Cardona GR, Urva S, Emmerson PJ, Holst JJ, DAlessio DA, Coghlan MP, Rosenkilde MM, Campbell JE, Sloop KW
doi:10.1016/s1521-6616(03)00206-7 Weymouth, L., Smith, A
doi:10.1053/jvet.2003.50066 10
Convenience: Pills are easy to carry and consume, while liquids may require measuring and can be less portable
Based on the results of clinical data, empagliflozin and dapagliflozin are now recommended for the treatment of HFpEF, as well as for HFrEF also in the absence of diabetes (McDonagh et al., 2021
Overall, these findings show that GLP-1R recycling is influenced by persistence of agonist binding within the endosomal compartment, resulting in enhanced insulin-releasing properties of fast-dissociating agonists which maintain an adequate population of cell surface receptors over prolonged periods
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