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(A) Structure of HGF consisting of a -chain (69 kDa) including four Kringle domains and a -chain (43 kDa) including a serine proteinase homology (SPH) domain, linked by disulfide bonds (S)

Together, they address both local tissue damage and systemic inflammation

A bottle punctured 30+ times for a multi-vial peptide cycle accumulates microbial entry events faster than the preservative load can suppress them

Its stability and broad applicability make it a useful tool in preclinical research

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Since these guidelines are preliminary, researchers should conduct initial dose-finding studies to identify the optimal range for their specific models