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Prior biochemical analysis has shown that the enzyme responsible for phosphorylation of S752 (S737 in isoform 1 studied in ref
Therefore, rapidly developing effective treatment strategies and vaccines are vital to mitigate those consequences
Together, these findings indicate that tau phosphorylation induced by palmitoyl-L-carnitine is mediated by GSK-3, CDK5, and calpain, which are activated by calcium overload
However, realizing broader societal impact requires addressing fundamental cost, access, and long-term sustainability challenges
Journal of Hand Surgery (European Volume)
