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7 The second, reflectance confocal microscopy (RCM), allows the in vivo microscopic visualization of the skin and mucosa, which provides highresolution horizontal views with an approximate depth of 200300 m
Cardiovascular outcome trials of tirzepatideSURPASS-CVOT and SUMMIThave shown encouraging signals, with SURPASS-CVOT meeting the prespecified criteria for non-inferiority for MACEs and a 16% reduction in all-cause mortality [86]
92 In one placebo-controlled trial that included 28 healthy older participants, 750 mg gotu kola extract daily for two months improved working memory and increased brain electrical activity during cognitive tasks, but neither 250 nor 500 mg daily had these effects
Cagrilintide as a standalone monotherapy is being evaluated in the RENEW Phase 3 program
Metabolite-metabolite and metabolite-gene interaction analysis To further explore the functional relationships among metabolites and their potential links to gene regulation, metabolitemetabolite and metabolitegene interaction networks were constructed using plasma metabolomic data from ASD and healthy control participants (Fig
2 , 2 GLP-1
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