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Blundell et al

During a subcutaneous injection, a short needle is used to inject a drug into the fatty tissue layer between the skin and the muscle, usually in specific areas of the thigh, arm, and abdomen

The specific length of the needle makes it foolproof to use the pen, as it's calibrated to give you the right dose at the right distance beneath the skin

They also communicate value as consumers know how expensive purchasing protein-heavy grocery items, like meat and protein powder, are in the grocery store

Although no significant difference in the incidence of GI AEs was observed, previous data suggest that GI AEs remain a clinically plausible cause for discontinuations [33]

Another factor is the packaging the medication is in