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The math is simple: you're adding roughly 0.5mg every two weeks, pausing at each level until the side effect picture is clear

Most Ab-based therapeutics are still of the IgG isotype and contain an IgG Fc fragment, and as such rely on FcRn for a long plasma half-life and favorable biodistribution

Needless to say, there seems to be evidence of both an association of low B12 and early greying, and a reversal of early greying following B12 supplementation

Instead of answering what medicine suppresses symptoms, we rather pay attention to what is missing in the body thats preventing it from calming down

Cuartero et al., 2019)