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The detail is contained within two recent publications in prestigious, peer-reviewed medical journals: Doctors at the University of North Carolina in America conducted a small clinical trial of GLP-1 in pouchees who had a high frequency of bowel movements but with a normal pouch (i.e., no inflammation)

Rest the affected area, rotate strictly within approved injection sites, and watch for infection warning signs such as spreading redness, warmth, pus, fever, and worsening pain

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The medications also lower A1C levels, reduce liver fat in non-alcoholic fatty liver disease, and decrease inflammation markers linked to chronic disease

Nature, 402:656-60

Over time, and with repeated access, that risk grows