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Tirzepatide works by mimicking two gut hormones, GLP-1 and GIP, which regulate blood sugar, slow digestion, and help control appetite

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In one trial for semaglutide, participants taking a 2.4 mg once-weekly dose lost 14.9% of their body weight over 68 weeks compared to a weight reduction of 2.4% in the placebo group

Some cases required hospitalization

Semaglutide reduced the risk of death from heart disease, nonfatal heart attack, and nonfatal stroke by 20 percent in people with established heart disease who were overweight or obese but who didnt have diabetes

A nonprofit named The Diabetes Link curates a list of options for at-home screening