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Side Effects and the Copper Uglies Explained GHK-Cu has a strong safety profile in topical research, but a small subset of users experience a transient phase known as the copper uglies. A 2023 clinical safety review covering 12 studies and 512 participants reported that the most common side effects of topical GHK-Cu were transient and mild
Ilic S, Brcic I, Mester M, Filipovic M, Sever M, Klicek R, et al
He's like, dude, of course
However, there are common mistakes that can impact both the effectiveness of the treatment and patient safety
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