Berberine may help reduce body weight modestly (about two to four pounds over several weeks) and lower HbA1c levels, but it lacks the robust, consistent results seen with GLP-1 medications like Ozempic, which can produce 15 to 20 percent body weight reductions in clinical trials. Can GLP-1 Supplements Help With Weight Loss
We examined the adult fat bodies in treated and untreated animals to see whether similar responses are present in our models
[1] Carnitine shuttle system [edit] The free-floating fatty acids, released from adipose tissues to the blood, bind to carrier protein molecules known as serum albumin that carry the fatty acids to the cytoplasm of target cells such as the heart, skeletal muscle, and other tissue cells, where they are used for fuel
The drugs are also effective in promoting weight loss if taken according to their treatment plan, which means patients should take the drugs continuously for at least 12 weeks
PLoS One 19, e0307428
So, well, first off, I will say as my mentor was dying, he died of cancer, sadly