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Pre-existing nutrient deficiencies
A 2022 study found that manual lymphatic drainage reduced arm circumference and improved quality of life in breast cancer survivors
But it also targets an additional hormone receptor (GIP)
Andrew Huberman And I went back and forth on this literature because I thought, "No, water would be better." But they compared water, two liters a day or a liter or more per day of diet soda, and it seems like it's a pretty good weight loss tool for people that would otherwise be drinking soda, or would otherwise be drinking just water, which really surprised me
Tirzepatide, a dual GIP/GLP-1 receptor agonist, represents the newest class of weight loss medications with remarkable clinical trial results from the SURMOUNT studies (Jastreboff et al., NEJM, 2022)
(2018, PLOS ONE ): transdermal dihydroberberine (a chemically modified form) applied in a pharmaceutical-grade cream with penetration enhancers achieved roughly 7x higher bioavailability than oral berberine in rats
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