These variable responses are consistent with GI adverse reactions documented in the SmPCs for approved GLP-1-based medicines (see, for example, the EMC SmPCs for Wegovy and Mounjaro)
If compounded semaglutide is left out of refrigeration for too long, several issues may arise: Degradation of Active Ingredients: The stability of the medication may be compromised, leading to a decrease in its effectiveness
Yet many professional skin care brands are still responding tactically, launching products, testing claims, or chasing Ozempic face messaging
The authors declare that they have no competing interests
10.1016/j.tig.2020.05.002 67 MacLaughlinK
Over the same period, public interest in these drugs exploded as well, with Google searches for GLP-1 increasing twentyfold