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Semaglutide can also lead to similar issues but may be milder for some users
This story was originally published July 8, 2024
Younger participants in the 25 to 40 age range tended to report fewer GI side effects and showed slightly faster adaptation during the dose escalation phase
In contrast, GLP-1R agonists are safer, and several studies have shown that GLP-1R agonists significantly improve cognitive impairment ( Figure 1 ) (25, 26, 8385)
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Preclinical signals regarding potential effects on thyroid C-cells (observed with GLP-1 agonists as a class), as well as theoretical questions about bone metabolism and cardiovascular function, are being monitored in ongoing trials
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