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From this solution, 1 mL is mixed with 0.5 mL of transformation solution (4.5 mM KCN and 0.45 mM K 3 [Fe(CN) 6 ] adjusted with 0.25 M potassium dihydrogen phosphate to pH 7.0)
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Besides, dual GLP-1/GIP receptor agonists (DA-JC4, DA5-CH, DA-JC1 and DA-CH3) reduced inflammation response, amyloid plaques and tau phosphorylation in brain, reversed memory loss, and enhanced synaptic plasticity in hippocampus of APP/PS1 mice (186, 234, 236, 238)
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