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In recent years, an additional surface cleft called BF3 (binding function 3) was found to allosterically regulate AF2 coactivator binding (Figure 3E) 86,87,88

While it shows promise for cognitive enhancement and neuroprotection, the lack of extensive research means that some potential risks may remain unknown

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Redox status and protein binding of plasma homocysteine and other aminothiols in patients with homocystinuria

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