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Smith HZ, Hollingshead CM, Kendall B

Metabolic changes included a reduction of the usage of muscle glycogen (i.e., its carbohydrate stores) during low-intensity exercise (consistent with an increase in lipid utilization) and streamlined glucose metabolism and mitochondrial flux during high-intensity exercise, leading to reduced anaerobic ATP production (which is what leads to lactic acid build-up in muscles)

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The 2017 Drug Testing and Analysis SAR review compiled the structural relationships across the GHRP class including Ipamorelin and related analogues (PMID 26811125)

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