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That pressure is what causes the classic symptoms: localized pain, radiating pain down a leg (sciatica) or arm, numbness, tingling, and muscle weakness

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Endogenously produced in the paraventricular and supraoptic nuclei of the hypothalamus and released from the posterior pituitary, oxytocin acts both peripherally and centrally

Estradiol regulates daily rhythms underlying diet-induced obesity in female mice