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Clinical Takeaways As the prevalence of obesity, insulin resistance, metabolic syndrome and associated health complications continue to rise, targeting GLP-1 activity has emerged as a promising strategy in improving cardiometabolic health and encouraging sustainable weight loss

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Patient selection for potential GLP-1 therapy in the context of binge eating requires careful clinical assessment

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Overdose and Toxicologic Considerations Although severe toxicity is uncommon, accidental overdose of GLP-1 receptor agonists is increasingly reported, most often due to injector pen errors