RapidFire MS Ultra-high throughput (1015 seconds per sample) for early-stage screening of large compound libraries, with sensitivity comparable to conventional LC-MS/MS
Investigators value this compound due to its specificity, stability, and consistent behavior in experimental models
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This aggressive metabolic shift, while beneficial for fat loss, places demands on the body that warrant additional support
Knockdown of BCAT1 causes accumulation of -KG, promoting EGLN1-mediated HIF1 protein degradation and leukemia-initiating arrest (Raffel et al., 2017)