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Considering a three-dimensional structural model for a complex of the human HGF-NK2 segment sandwiched by c-met receptor molecules (see supplementary Figure 3, re-produced from PDB ID 7MO7 67 , it is hypothesized that the disulfide bonds, notably Cys149-Cys189 and Cys177-Cys201 localized internally just behind Y198, are the targets of LASSS
doi: 10.5194/bg-17-3891-2020 40 SchrollM.LenhartK.BenderT.HttenP.RudolphA.SrensenS.et al
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The resulting complex was additionally minimized as described above
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