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One proposed mechanism involves adenylyl cyclase activity, which could raise cyclic AMP (cAMP) levels and activate protein kinase A (PKA)

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This effect is shared with other GHRPs and contributes to the synergistic GH release observed when GHRPs are combined with GHRH analogs

Vural H, Demirin H, Kara Y, Eren I, Delibas N

[Google Scholar] Simultaneous 3-Nitrophenylhydrazine Derivatization Strategy of Carbonyl, Carboxyl and Phosphoryl Submetabolome for LC-MS/MS-Based Targeted Metabolomics with Improved Sensitivity and Coverage