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Th17/IL-17A axis is critical for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc): SSc patients with high levels of serum IL-17A exhibit reduced lung functions and increased prevalence of PAH

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The study also showed that semaglutide lowered the risk of major heart problems, like heart attack or worsening heart failure, by 20% in people without diabetes who had cardiovascular disease, overweight, or obesity