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Now, there is encouraging evidence that their effect on craving and satiety may help to treat substance use disorders
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Many prescribe other brands of semaglutide, such as Ozempic and Rybelsus, off-label (using a drug that is FDA-approved for a different reason)
You shouldnt take tirzepatide medications or Wegovy if you have: A personal or family history of medullary thyroid carcinoma (MTC) A history of multiple endocrine neoplasia syndrome type 2 (MEN 2) A serious allergic reaction to tirzepatide, semaglutide , or any of the ingredients in these medications Your clinician will determine if GLP-1 medications are right for you if you have a history of: Pancreatitis , kidney problems, or gallbladder disease, including gallstones Diabetic retinopathy Gastroparesis or other serious digestive conditions Tirzepatide and Wegovy are also not for people who are pregnant, planning to become pregnant, or breastfeeding
The standard Wegovy protocol produces roughly 35 pounds of weight loss over 16 months
N Engl J Med 389:2221-32
