13 In addition to being recommended in patients with ASCVD, GLP-1 receptor agonists are recommended for consideration as an add-on to metformin in patients without established ASCVD in whom there is a compelling need to minimize hypoglycemia, minimize weight gain, or promote weight loss
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GLP-1 is secreted in the small intestine and relays messages to other areas in our body
Furthermore, a study showed that GIP infusion caused an increase in blood glucose levels, probably because of the increase in glucagon