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Over the past few years, GLP-1 medications for weight loss such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) have surged in popularity, including among older adults

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A vibratome (Leica VT1200S, Leica Biosystems) was used to obtain 250 m thin acute brain slices containing Arc, identified by well-known landmarks

Quick Summary GLP-1 medications are FDA-approved prescription drugs for type 2 diabetes and/or chronic weight management

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