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The FDA enforcement-discretion period that allowed mass compounding during the tirzepatide shortage ended on March 19, 2025 for 503B outsourcing facilities and February 18, 2025 for 503A pharmacies
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None of these routes are approved for clinical or therapeutic use in humans, and all remain experimental
The diagnosis is made based on symptom report alone for most people
Common Ozempic side effects include: Weight loss Gastrointestinal symptoms, such as nausea, constipation, diarrhea, and abdominal pain Eye symptoms, such as diabetic retinopathy Low blood sugar, characterized by lightheadedness Injection site reactions, such as pain or redness Serious side effects include: Thyroid tumors Angioedema (swelling of tissues in the face, eyes, and lips) Acute kidney injury Worsening of kidney disease Pancreatitis (inflammation of the pancreas) Gallbladder inflammation (cholecystitis) Cholelithiasis (gallstones) Gastroparesis (stomach paralysis) Syncope (fainting and loss of consciousness) Serious side effects should be reported to a healthcare provider immediately
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