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One solution in these cases is getting B12 way of an injection

In the study by Neelakantan et al

In the fourth and last stage of B12 deficiency, clinical manifestations are experienced by the individual including macrocytic anemia (a form of anemia in which red blood cells are larger than usual, hence the term macro) and, if left untreated, irreversible neurological damage

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Research is ongoing in this area for individuals without a deficiency, but if you have a deficiency, vitamin B12 injections may help fight fatigue, weakness, and other symptoms

simultaneous recording of heart rate, oxygen saturation, respiratory analysis and sleep time