Neurogastroenterol Motil 32(2):e13738
As a triple receptor agonist targeting GLP-1R, GIPR, and glucagon receptors simultaneously, it is investigated for how this multi-receptor engagement may influence metabolic signaling differently from dual or single receptor agonists
Some of the commonly reported side effects include: Nausea Diarrhea Vomiting Constipation Abdominal pain Loss of appetite Headache Fatigue Dizziness These side effects are usually mild to moderate in intensity and tend to improve over time as the body adjusts to the medication
These warrant dose reduction or temporary pause
On the contrary, the APAP group showed enhancement of blue granules of hemosiderin in hepatocytes, indicating iron deposition
Guez S, Chiarelli G, Menni F, Salera S, Principi N, Esposito S