The significant HR (0.88) was determined to be similar for those with or without previous CVD and in those with A1C less than or greater than 7.2%, demonstrating GLP-1 RAs that reduce CV outcomes should be considered in patients across a wide range of A1C values and in those with CV risk factors but without established CVD
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Clinical trials show slightly higher average weight loss with tirzepatidearound 20-25% of body weight
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Biomol Concepts 15:20220038 Kyei G, obhani A, Nekonam S, Shabani M, Ebrahimi F, Qasemi M, Salahia E, Fardina A (2020) Assessing the effect of MitoQ10 and vitamin D3 on ovarian oxidative stress, steroidogenesis and histomorphology in a DHEA-induced PCOS mouse model