For most individuals this is dinner, making late-afternoon dosing (4-6pm) ideal
Causal factors for knee, hip, and hand osteoarthritis: a Mendelian randomization study in the UK biobank
The drugs fixed that part
Interestingly, the same study found that, in rats, tirzepatide suppressed lipid intake without affecting sucrose (carbohydrate) consumption in a choice-based assay, implying that the effects of these medications may be macronutrient specific (Geisler et al., 2023)
Pills may offer a lowercost entry point for people starting GLP1 treatment
These predispositions should be interpreted with a qualified healthcare provider in the context of your clinical history, biomarker data, and lifestyle factors