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Overall, it would appear that the abundance of GSTs and their predominantly high activity with JS-K would cause the rapid biotransformation of the prodrug in most tissues

Although few of them have received the regulatory approval for routine clinical use, a variety of new OA drugs have shown promising results in clinical trials (Table 2)

Future research should focus on exploring the use of combination therapy in cancer treatment

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PMID: 37108769 Int J Mol Sci Ferroptosis and Apoptosis Are Involved in the Formation of L-Selenomethionine-Induced Ocular Defects in Zebrafish Embryos