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At Derma Clinic Kathmandu , we get this question from patients almost every week

Do not use during pregnancy or breastfeeding without medical advice

Currently, clinical trials are underway to evaluate the safety and efficacy of tirzepatide in patients with heart failure

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More than 100 million American adults are obese, and the drugs may eventually be rolled out to people without diabetes or obesity, as they seem to tame addictions beyond food appearing to make cocaine, alcohol and cigarettes more resistible

PLoS ONE 9(8):e105757