Safety and Side Effects Semaglutide, whether commercial or compounded, can cause side effects such as: Nausea Vomiting Diarrhea or constipation Fatigue Headache Serious (but rare) side effects may include: Pancreatitis Gallbladder disease Thyroid tumors (seen in animal studies) A gradual dose escalation and provider monitoring are critical to minimize risks
Cynthia Maxwell and reviewed by First Exposure Medical Review Team
In a 2026 podcast interview, Huberman called retatrutide "the peptide that's going to change everything" and described it as a triple agonist of GLP-1, glucagon, and GIP receptors
After Plasmage treatment, you may experience minor swelling for two to three days, along with light crusting, which are both temporary and manageable
Disclaimer: Disclaimer : These statements have not been evaluated by the Food and Drug Administration
however, they also show that skin-related adverse events do occur and may be underrecognized in clinical practice, Fat told Healio