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Biochemistry 28 , 72987305 (1989)
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This glucose-dependent mechanism means insulin secretion occurs primarily when blood sugar is elevated, reducing hypoglycemia risk compared to some other diabetes medications
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Compounding may be appropriate when: A required dose, concentration, or formulation is not commercially available An FDA-approved drug is in a temporary shortage A patient has a documented allergy or intolerance to an inactive ingredient Compounding is intended to address medical necessity , not convenience, mass substitution, or price alone