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Further assessment of this combination of inhibitors is warranted, including other USP14 inhibitors and other XIAP-targeting IAP antagonists, as well as in vivo models to assess for toxicities and pre-clinical efficacy
Timely intervention can be lifesaving, as the sooner blood flow is restored, the less damage will occur to the heart muscle
At the same time, it exhibits a favorable safety profile in animal studies
Standard saline or sterile water lacks this preservation, limiting solution stability to days rather than weeks
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